This database is in development
Nuclease bacteriocins are antimicrobial proteins produced by bacteria that are capable of directly inhibiting closely related bacterial strains. In bacteriocin producing strains, co-expression of the dedicated immunity gene, downstream of the bacteriocin prevents self-inhibition. Nuclease bacteriocins have become drug candidates for narrow spectrum antibiotics, anti-cancer drugs and food preservatives.
NucleBact allows the phylogenetic analysis of nuclease bacteriocins and immunity sequences along with the prediction of bacteriocin susceptibility among γ-proteobacteria. Nuclease bacteriocins (BCIN) and immunity sequences (IMM) have been uploaded into the NucleBact database using the nuclease bacteriocin pipeline developed by Sharp et al. 2017 PLoS Comput Biol 13:e1005652.
Database curated by annapaula.correia
zoo.ox.ac.uk (Annapaula Correia).